Introduction:

This service offers identification and quantification of the proteome in your complex samples without chemical modifications. The data generated by this service is a complete catalogue of the proteins present in your samples together with a statistical analysis result demonstrating the abundance of each identified protein in your samples. This service enables researchers to compare the proteome difference in their treated vs untreated, diseased vs normal, over-expressed vs control, gene silenced vs control, knockout vs wild type, mutant vs wild type groups, etc, with a relatively good accuracy. For better accuracy and reproducibility, please refer to our TMT Labeling Quantification Service. ​ Your samples (several test groups and control group) will be digested with Trypsin and cleaned by C18 cartridges. To improve the sensitivity, we suggest the basic Reverse Phase LC (bRPLC) to further fractionate the cleaned sample into 96 fraction and then pooled to 24 fractions, which are subject to 24 Mass Spectrometry Analysis runs by the world’s most advanced Orbitrap LC-MS/MS system.

Data analysis, including data validation, visualization and quantification, are performed with commercial softwares and Complete Omics’ unique R packages and scripts. Report will be sent to you in Excel format as well as a summary in PDF format. We will also provide you any details you need for your papers’ MATERIALS AND METHODS section. We will make sure you understand your result and help you with your paper writing with free follow-up services.

Sample types we accept:

1, 2D gel spots, SDS-PAGE bands

2, Cell Lysates and Tissue Lysates

3, Biofluids, such as plasma*, serum*, saliva, tear, etc.

*We provide High Abundance Protein Depletion Service to significantly (100-500 folds) increase the depth of your biofluid proteomics analysis by removing top abundant proteins from your samples. Read more for details​.

4, FFPE slide/ FFPE extract

5, Customized sample types (please contact us to discuss)

Complete Omics Inc. Proudly Welcomes Proteomics Luminary Dr. Hui Zhang as Chief Scientific Officer

January 12, 2024 | BALTIMORE –  Complete Omics’ Clinical Proteomics team are thrilled to announce that Dr. Hui Zhang, a distinguished figure in the realm of proteomics, has joined the…

Read more

Securing a Brighter Future: Celebrating Our Investment from Qiming Venture Partners

November 25, 2023 | BALTIMORE –  Complete Omics management team are thrilled to announce a significant milestone for our company – a recent investment by Qiming Venture Partners. This partnership…

Read more

Complete Omics Inc. Founder Qing Wang Featured on Wharton Business School’s Official Website

July 27, 2023 | BALTIMORE –  Complete Omics is proud to announce a momentous occasion for Complete Omics Inc.: our visionary founder, Qing Wang, has been featured on the prestigious…

Read more

Some of our impacts