Introduction:

Depletion is the process of removing high abundance proteins from body fluid samples. Body fluids are highly complicated biological samples that their proteomes are composed of virtually all proteins encoded by the genome and more importantly, the abundances of different proteins vary dramatically across 100 million to 1000 billion folds. Without depletion, high abundance proteins will always dominate the proteomic profiling of a body fluid sample.

Over the years, Complete Omics has optimized a clinical applicable pipeline and it is composed of both a chemical-based depletion step and an antibody-based depletion step.  We routinely reach the depth of detecting and quantifying over 200,000 different peptides in a 10ul plasma sample.

 

Sample types we accept:

1, Biofluids, such as plasma, serum, saliva, tear, etc.

2, Customized sample types (please contact us to discuss)

Collaboration with Columbia University

Mar 30, 2022 | BALTIMORE –  Complete Omics’ Clinical Proteomics team announced a collaboration with Professor Kam W. Leong, Samuel Y. Sheng professor of Biomedical Engineering, and his team from…

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Collaboration with Tel Aviv University

Mar 20, 2022 | BALTIMORE –  Complete Omics’ Clinical Proteomics team announced a collaboration with Professor Miguel Weil from Department of Cell Research and Immunology at the Tel Aviv University…

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Detecting and Absolutely Quantifying Patient-specific Neoantigens from Limited Input of Biopsy Sample — An Integrated Pipeline for Neoantigen-targeted Cancer Treatments

Neoantigens derived from HERVs represent a new group of cancer therapeutic targets. In a collaborating project, Complete Omics identified and quantified HERVs derived neoantigens and provided solid evidence for developing…

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Some of our impacts