Depletion is the process of removing high abundance proteins from body fluid samples. Body fluids are highly complicated biological samples that their proteomes are composed of virtually all proteins encoded by the genome and more importantly, the abundances of different proteins vary dramatically across 100 million to 1000 billion folds. Without depletion, high abundance proteins will always dominate the proteomic profiling of a body fluid sample.

Over the years, Complete Omics has optimized a clinical applicable pipeline and it is composed of both a chemical-based depletion step and an antibody-based depletion step.  We routinely reach the depth of detecting and quantifying over 200,000 different peptides in a 10ul plasma sample.


Sample types we accept:

1, Biofluids, such as plasma, serum, saliva, tear, etc.

2, Customized sample types (please contact us to discuss)

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