Introduction:

NGS using FFPE slide is proven to be a very valuable resource for retrospective studies across long period of time and providing opportunity to correlate disease state, outcome and tissue morphology to genotype (DNA) and/or expression (RNA). However, it is challenging to get intact information from FFPE samples because of the severe degradation, damage and biological modification occured within such samples during years of storage in the air at variable ambient temperatures. With Complete Omics’ unique MyGene™-UltimateSens™ FFPE NGS service, NGS sequencing can be accomplished with as few as one FFPE slide.

The quest to trace the roots of the human race has long motivated scientists into the sequences of ancient DNA extracted from skeletal remains unearthed by archaeologists. However, ancient DNA typically bears signs of fraying and fragmentation inflicted by exposure to the elements over great gulfs of time, posing challenges to a successful NGS sequencing. Complete Omics’ MyGene™-UltimateSens™ was initially invented to concstuct NGS libraries with human remains 30,000 years old. Our genomics team is specialized in handling toughest ancient and damaged DNA samples and provide you best result in the field of NGS sequencing.

In a NGS seqeuncing project, it is very common to fall into the situation of being lack of enough materials for sequencing. Samples that are collected for deep study, such as NGS sequencing, are usually precious with very limited amount available. Sometimes, you have enough materials to start with, however, after several rounds of library preparations, you still can not get NGS datasets with desired quality, and now only very few samples are left for further test. It is the time to contact Complete Omics and learn more about our MyGene™-UltimateSens™ NGS technology, a NGS library construction method WITHOUT EXCESSIVE PCR AMPLIFICATION.

Sample types we accept:

1, Purified DNA / RNA samples

2, Cell Lysates and Tissue Lysates

3, Biofluids, such as plasma*, serum*, saliva, tear, etc.

4, FFPE slide/ FFPE extract

5, Fossil

6, Customized sample types (please contact us to discuss)

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